منابع مشابه
L-dopa therapy in Parkinson's disease.
The gait of normal subjects was examined electromyographically and the pattern was altered during preferential blockade of large nerve fibres to alternating activity in flexor and extensor muscles. The EMG activity was disrupted more in flexor than extensor muscles by preferential ischaemic blockade. Normal gait was associated with flexor contraction only when the foot was lifted and placed on ...
متن کاملL-dopa
Oleh Hornykiewicz was born in 1926 in Sykhiw, Poland (now Ukraine). In 1951, he received his M.D. degree from the University of Vienna and joined the faculty of his alma mater the same year and has worked there ever since. He also served for twenty years as chairman of the Institute of Biochemical Pharmacology. In 1967, he began a long association with the University of Toronto in Canada and, i...
متن کاملMolecular Effects of L-dopa Therapy in Parkinson’s Disease
Parkinson's disease (PD) is one of the most common neurological diseases in elderly people. The mean age of onset is 55 years of age, and the risk for developing PD increases 5-fold by the age of 70. In PD, there is impairment in both motor and nonmotor (NMS) functions. The strategy of PD motor dysfunction treatment is simple and generally based on the enhancement of dopaminergic transmission b...
متن کاملL-Dopa and Behavior
to include the "why" of procedures, but rather presents step-by-step instructions and recipes for the bench technologist. The first of the three sections deals with biochemical identification tests, from acetate utilization to Voges-Proskauer. Each includes descriptions of purpose, principle, mechanisms, equipment and reagents, method, and interpretation. The format is short, lucid, and informa...
متن کاملEffects of L-dopa during Auditory Instrumental Learning in Humans
The dopaminergic neurotransmitter system is critically involved in promoting plasticity in auditory cortex. We combined functional magnetic resonance imaging (fMRI) and a pharmacological manipulation to investigate dopaminergic modulation of neural activity in auditory cortex during instrumental learning. Volunteers either received 100 mg L-dopa (Madopar) or placebo in an appetitive, differenti...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5710.639